The Kansas Multi‐Tier System of Supports and Alignment (MTSS): Research Base document has been created to assist in the understanding of the research base that underlies the principles and practices of MTSS. This document is not intended to be a comprehensive review of all the research that supports MTSS but a highlight of some of the main pieces of work that have been done to provide a starting point for further research by any interested individual. Also, this document will never truly be ‘completed’ since the research available that guides our educational practices is growing on a daily basis. This document will be updated periodically in an attempt to keep current with any new findings that further our understanding and guide our thinking to best provide support to all students so they will learn.